DERIVATIVES OF N-(ARYLAMINO) SULFONAMIDES INCLUDING POLYMORPHS AS INHIBITORS OF MEK AS WELL AS COMPOSITIONS, METHODS OF USE AND METHODS FOR PREPARING THE SAME
The present invention relates to mek inhibitor N-(the 2-virtue is amino) arylsulfonamide compounds, it comprises the crystalline polymorph that demonstrates particular powder X-ray diffractogram and/or specific differential scanning amount thermal map.The invention still further relates to the pharmaceutical composition that comprises compound described herein and the using method of compound as herein described and composition, it is included in the purposes that treats and/or prevents in cancer, excess proliferative disease and the inflammatory patients condition.The invention still further relates to preparation compound as herein described and method for compositions.
