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Difluoromethylene compounds
专利权人:
佐藤製薬株式会社
发明人:
永井 啓太,馬場 基彰,藤岡 真一,長澤 考,高橋 博文,近藤 江里,十河 祥恵,田中 健一,伊藤 良樹
申请号:
JP2014527032
公开号:
JP5965484B2
申请日:
2013.07.26
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
The present invention relates to a compound having an URAT1 inhibitory activity, and to an URAT1 inhibitor, a blood uric acid level-reducing agent and a pharmaceutical composition containing the compound. More specifically, the present invention relates to a compound represented by the formula (I): wherein R 1 is -Q 1 -A 1 or the like; R 2 is a hydrogen atom, a halogen atom, a lower alkyl group or the like; W 1 , W 2 , W 3 and W 4 are each independently a nitrogen atom or a methine group optionally having substituents, or the like; X and Y are each a single bond, an oxygen atom or the like; Z is a hydroxyl group or COOR 3 or the like.
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