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COMPOSÉS POUR LA TOMOGRAPHIE PAR ÉMISSION DE POSITRONS
专利权人:
Purdue Research Foundation;Endocyte, Inc.
发明人:
申请号:
EP14861854.9
公开号:
EP3069147A4
申请日:
2014.11.13
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Described herein are compounds, compositions, and methods for diagnosing and/or monitoring pathogenic disease using positron emission tomography. Also described are conjugates of the formula B-L-P, wherein B is a radical of a targeting agent selected from vitamin receptor binding ligands (such as folate), PSMA binding ligands, or PSMA inhibitors; L is a divalent linker comprising aspartic acid, lysine, or arginine, and P is a radical of an imaging agent or radiotherapy agent, such as a radionuclide or radionuclide containing group, or a radical of a compound capable of binding a radionuclide, such as a metal chelating group.
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