Pizza, Maria-grazia,Scarselli, Maria,Rappuoli, Rino,Giuliani, Marzia Monica,Arico, Maria
申请号:
AU2013202472
公开号:
AU2013202472A1
申请日:
2013.04.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013202472A120130502.pdf#####ABSTRACT fHBP is a protein in Neisseria meningitidis. Three families of fHBP are known. To increase the ability of a fHBP protein to elicit antibodies that are cross-reactive between the families, fHBP is selected or engineered to have a sequence which can elicit broad-spectrum bactericidal 5 anti-meningococcal antibodies after administration to a host animal.