Pizza, Mariagrazia,Scarselli, Maria,Rappuoli, Rino,Giuliani, Marzia Monica,Arico, Maria
申请号:
AU2010288240
公开号:
AU2010288240A1
申请日:
2010.08.27
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
fHBP is a protein in . Three families of fHBP are known. To increase the ability of a fHBP protein to elicit antibodies that are cross-reactive between the families, fHBP is selected or engineered to have a sequence which can elicit broad-spectrum bactericidal anti-meningococcal antibodies after administration to a host animal.