Kurt Iver Kamrud,Maung Nyan Win,Nathaniel Stephen Wang,Jason L. DeHart
申请号:
US15831230
公开号:
US20180171340A1
申请日:
2017.12.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure generally relates to nucleic acid molecules for use in regulating gene expression. Disclosed herein include nucleic acid molecules containing one or more structural elements of the viral capsid enhancer operably linked to a coding sequence of a gene of interest. In some embodiments, the viral capsid enhancer comprises a Downstream Loop (DLP) from a viral capsid protein, or a variant of the DLP.