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КОМПОЗИЦИИ ДЛЯ ИММУНИЗАЦИИ ПРОТИВ STAPHYLOCOCCUS AUREUS
专利权人:
НОВАРТИС АГ (CH)
发明人:
БАНЬОЛИ Фабио (IT),БЬЯДЖИНИ Массимильяно (IT),ФЬЯСКИ Луиджи (IT),ГРАНДИ Гвидо (IT),МИШРА Рави (IT),НОРАИС Натали (IT),СКАРСЕЛЛИ Мария (IT)
申请号:
RU2013154779/15
公开号:
RU2013154779A
申请日:
2013.12.10
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. An immunogenic composition comprising an antigen sta006 for use in a method of protecting a mammal S.aureus infection, wherein the antigen sta006: (i) can induce antibody which recognizes SEQ ID NO: 42 and (ii) comprises the amino acid sequence: (a) having 50% identity or more of SEQ ID NO: 42 and / or (b) comprising a fragment of at least, n consecutive amino acids of SEQ ID NO: 42, wherein n is 7 or bolee.2. An immunogenic composition for protecting a mammal from infection S.aureus, comprising sta006 antigen and an adjuvant, wherein the antigen sta006: (i) can induce antibody which recognizes SEQ ID NO: 42 and (ii) comprises the amino acid sequence: (a) having 50% identity or more of SEQ ID NO: 42 and / or (b) comprising a fragment of at least, n consecutive amino acids of SEQ ID NO: 42, wherein n is 7 or bolee.3. The composition of claim 1, further comprising: an antigen sasD, antigen clfB and antigen sdrC antigen esxA, antigen esxB and antigen hla antigen esxA, antigen esxB and antigen sta011 antigen esxA, antigen esxB, antigen isdA, antigen sta011 and antigen spa. antigen esxA, antigen esxB, antigen Hla and antigen sta011 antigen hla, antigen isdA and antigen sta011 antigen esxA, antigen esxB and isdA antigen the antigen Hla and antigen sta011 antigen esxA and antigen esxB antigen spa and antigen sta011 antigen esxA, antigen esxB, isdA antigen and antigen sta011 antigen sta011 antigen esxA, antigen esxB, antigen ISDA and antigen clfB antigen sta011 and antigen sta019 antigen esxA, antigen esxB, antigen hla and antigen clfB antigen sta011, antigen sta019, and the antigen hla antigen esxA, antigen esxB, antigen sta011 and antigen clfB antigen spa, antigen esxA, antigen esxB and antigen sta011 antigen esxA, antigen esxB, antigen sta011 and antigen sta019 antigen esxA, antigen esxB, isdA antigen and antigen sdrD iliantigen Hla, an antigen and an antigen spa sta011 wherein the antigen sta011 (i) may be induced1. Иммуногенная композиция, включающая антиген sta006
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