A moisture-resistant multi-phase orthopedic system and method including a single layer, three-dimensional knitted fabric having an open structure for providing enhanced moisture transfer from the skin outwardly into the atmosphere and a flap carried by the body and movable between an open position and a closed position overlying a part of the cast body to be applied to a treatment area of the limb. The flap is adapted to cover and retain between the cast body and the flap the splint worn by the patient during the initial treatment phase in the same position as the location of the splint during the initial treatment phase.
