Use of sugar-alcohols in tibolone compositions

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专利权人:

Mithra Pharmaceuticals S.A.

发明人:

Jaspart, Séverine

申请号：

AU2017260799

公开号：

AU2017260799A1

申请日:

2017.05.04

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present invention relates to the use of a sugar-alcohol for stabilizing tibolone in a solid dosage form. The invention also pertains to a pharmaceutical composition, in particular a solid dosage form such as a tablet, comprising tibolone and a sugar-alcohol and a non-sugar-alcohol diluent, wherein the weight ratio of the sugar-alcohol to the non-sugar-alcohol diluent is comprised between 4:1 and 1:4, and a method for preparing the same.

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