In a liquid ejection control device, an operation unit includes an energy dial for inputting an energy instructing value related to kinetic energy of a pulsed liquid jet ejected from a liquid ejection device, and a repetitive frequency dial for inputting a repetitive frequency instructing value related to the number of times ejection of the pulsed liquid occurs per unit time. In addition, a controller includes a voltage magnitude setting section that sets voltage magnitude of the drive voltage waveform such that the kinetic energy becomes the energy instructing value, based on a rising index value related to rising of the drive voltage waveform and the repetitive frequency instructing value.