In a liquid ejection control device, an operation unit includes: a kinetic energy dial for inputting a kinetic energy instructing value related to kinetic energy of a pulsed liquid jet ejected from a liquid ejection device and a repetitive frequency dial for inputting a repetitive frequency instructing value related to the number of times of ejection of the pulsed liquid jets per unit time. In addition, a controller includes a voltage magnitude setting section that sets voltage magnitude of the drive voltage waveform such that the kinetic energy becomes the kinetic energy instructing value, based on a rising index value related to rising of the drive voltage waveform and the repetitive frequency instructing value.