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FORME PHARMACEUTIQUE INVIOLABLE COMPORTANT UN POLYMÈRE ANIONIQUE
专利权人:
GRÜNENTHAL GMBH
发明人:
申请号:
EP11760397.7
公开号:
EP2611425B1
申请日:
2011.09.01
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
A pharmaceutical dosage form and method of using same, the pharmaceutical dosage form exhibiting a breaking strength of at least 500 N, said dosage form containing a pharmacologically active ingredient (A); a physiologically acceptable polymer (B) obtainable by polymerization of a monomer composition comprising an ethylenically unsaturated monomer bearing an anionic functional group, in protonated form or a physiologically acceptable salt thereof; a polyalkylene oxide (C) having a weight average molecular weight of at least 200,000 g/mol, wherein the content of the polyalkylene oxide (C) is at least 20 wt.-%, based on the total weight of the dosage form; wherein the pharmacologically active ingredient (A) is present in a controlled-release matrix comprising the polymer (B) and the polyalkylene oxide (C).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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