FORME GALENIQUE INVIOLABLE POUR DES OPIOIDES SENSIBLES A L'OXYDATION

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专利权人:

GRUENENTHAL GMBH

发明人:

BARTHOLOMAEUS, JOHANNES,GEISSLER, ANJA,BERTRAM, ULRIKE,GRIESSMANN, KORNELIA,BICANE, FATIMA

申请号：

CA2767888

公开号：

CA2767888C

申请日:

2010.07.21

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising - an opioid (A), - - a free physiologically acceptable acid (B) in an amount of from 0T001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, and - a polyalkylene oxide (C) having a weight average molecular weight Mw of at least 200,000 g/mol.

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