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Fused substituted aminopyrrolidine derivative
专利权人:
Hisashi Takahashi;Makoto Takemura;Satoshi Komoriya;Takahiro Kitamura;Hiroaki Inagaki;Kenichi Yoshida;Rie Miyauchi;Masatoshi Nagamochi;Takashi Odagiri;Toshifumi Tsuda;Kiyoshi Nakayama
发明人:
Hisashi Takahashi,Satoshi Komoriya,Takahiro Kitamura,Takashi Odagiri,Hiroaki Inagaki,Toshifumi Tsuda,Kiyoshi Nakayama,Makoto Takemura,Kenichi Yoshida,Rie Miyauchi,Masatoshi Nagamochi
申请号:
US12459612
公开号:
US20130029977A9
申请日:
2009.07.02
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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