The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.本發明係關於新穎CCR2(CC趨化因子受體2)拮抗劑以及其用於提供用以治療病況及疾病,尤其用於治療如哮喘及COPD之肺部疾病之藥物的用途。