The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.本發明係關於一種針對CCR2(CC趨化因子受體2)之新穎拮抗劑,及其提供治療病狀及疾病、尤其肺病(如哮喘及COPD)之藥物的用途。