Patrick J. Sinko,Jieming Gao,Manjeet Deshmukh,Xiaoping Zhang,Matthew S. Palombo,Sherif Ibrahim
申请号：
US13296203
公开号：
US20120183621A1
申请日:
2011.11.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Non-Small Cell Lung Carcinomas (NSCLCs) are treated with Gel Micro-Particles (GMPs) that passively accumulate in the lungs and contain Nano-Particles (NPs) combining one or more therapeutic agents that are cytotoxic to the NSCLC with one or more NSCLC active targeting ligands, as well as one or more other optional agents that increase cellular uptake, enhance the pro-apoptotic effect of the chemotherapeutic agent(s), and the like. NPs targeting other cancer cells are also disclosed, as well as NP-containing GMPs that reduce the occurrence of tumor metastasis.
