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FORMULATIONS DE SOLUTION DE BENDAMUSTINE
专利权人:
Navinta; LLC
发明人:
申请号:
EP17847529.9
公开号:
EP3506898A4
申请日:
2017.08.31
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Liquid pharmaceutical formulation of Bendamustine that include bendamustine active pharmaceutical ingredient, N,N-Dimethylacetamide, and water in an amount of about 0.3% to 40%. The active pharmaceutical ingredient is Bendamustine, a pharmaceutically acceptable salt, and/or a hydrate form thereof, preferably Bendamustine HCl monohydrate. The formulations contain 20-200 mg/mL Bendamustine. The formulations are stable upon long term storage at refrigerated conditions. They can be administered to treat neoplastic conditions without reconstituting prior to administration.
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