Shaomeng Wang,Haibin Zhou,Jianfeng Lu,Liu Liu,Jeanne Stuckey,Liangyou Rui,Yi Sun
申请号：
US15949799
公开号：
US10500194B2
申请日:
2018.04.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Small molecule covalent inhibitors of DCN1 and compositions containing the same are disclosed. Methods of using the DCN1 covalent inhibitors in the treatment of diseases and conditions wherein inhibition of DCN1 provides a benefit, like oxidative stress-related diseases and conditions, neurodegenerative diseases and conditions, metabolic disorders, and muscular nerve degeneration, also are disclosed.
