THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
发明人:
KERR, WILLIAM,GUMBLETON, MATTHEW
申请号：
CA2986319
公开号：
CA2986319A1
申请日:
2015.06.17
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to the use of SHIP I inhibitors and pan-SHIP1/2 inhibitors in various methods, including, without limitation, a method of inhibiting SHIP to induce broad activation of natural killer (NK) cells to treat various diseases. In one aspect, the present invention relates to a method of activating natural killer (NK) cells in a subject suffering from an illness or condition for which NK cells provide a host defense. In one embodiment, this method involves administering a safe and effective amount of a SHIP1 inhibitor or a pan-SHIP 1/2 inhibitor to the subject.
