THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
发明人:
WILLIAM KERR,ROBERT BROOKS
申请号:
US16438626
公开号:
US20200129523A1
申请日:
2019.06.12
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to the use SHIP inhibitors to induce expression of granulocyte colony stimulating factor (G-CSF) in a subject, thereby promoting expansion of hematopoietic and mesenchymal stem cells. The present invention generally relates to new uses of SHIP inhibitors for therapeutic purposes. More particularly, the present invention relates to the use of SHIP inhibitors, including, without limitation, SHIP and/or pan-SHIP1/2 inhibitors, for the inhibition of SHIP to induce expression of granulocyte colony stimulating factor (G-CSF) to treat various-diseases or conditions.