Ugur SAHIN,Özlem TÜRECI,Michael KOSLOWSKI,Rita MITNACHTKRAUS
申请号:
MX2015005367
公开号:
MX357010B
申请日:
2009.09.16
申请国别(地区):
MX
年份:
2018
代理人:
摘要:
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast Cancer, lung Cancer, gastric Cancer, ovarian Cancer, hepatocellular Cancer, colon Cancer, pancreatic Cancer, esophageal Cancer, head & neck Cancer, kidney Cancer, in particular renal cell Carcinoma, prostate Cancer, liver cancer, melanoma, sarcoma, myeloma, neuroblastoma, placental choriocarcinoma, cervical cancer, and thyroid Cancer, and the metastatic forms thereof. In one embodiment, the rumor disease is metastatic cancer in the lung.La presente invención se refiere a un anticuerpo producido, o que se obtiene de un clon depositado bajo el número de acceso DSMACC2944, una forma quimerizada o humanizada del mismo.