The Invention provides Antibodies that bind to ly75. Also provided are Nucleic Acid molecules that encode Antibodies, Expression Vectors, host cells and Methods for expressing Antibodies.The Antibodies can be used for the treatment of cancer, including pancreatic cancer, ovarian cancer, Breast Cancer, colorectal cancer, esophagus cancer, Skin Cancer, Thyroid cancer, Lung Cancer, bladder cancer, Multiple Myeloma and LymphomaLa invencion proporciona anticuerpos que se unen a LY75. Tambien se proporcionan moleculas de acido nucleico que codifican los anticuerpos, vectores de expresion, celulas hospedadoras y procedimientos para expresar los anticuerpos. Los anticuerpos se pueden usar para el tratamiento del cancer, incluyendo cancer de pancreas, cancer de ovario, cancer de mama, cancer colorrectal, cancer de esofago, cancer de piel, cancer de tiroides, cancer de pulmon, cancer de vejiga, mieloma multiple y linfoma