Christopher E. Pelloski,James L. Sommerfeld,Kathryn Bondra,Lanchun Lu
申请号：
US13834025
公开号：
US20140270076A1
申请日:
2013.03.15
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present application relates to rodent radiation device that enables simultaneous radiation treatment of a plurality of small animals such as mice with localized radiation therapy. The device can provide clinically-relevant homogeneous radiation dosing and scheduling to a plurality of small animals or other in vivo cancer models simultaneously. Specifically, the multi station/unit design of the device allows for rapid loading of anesthetized small animals into radiation shield chambers that absorbs over 95% of the delivered dose and protects the remainder of the untreated animal, allowing for more clinically accurate recapitulation of radiotherapy regimens. In one embodiment, a total of 40-50 Gy is delivered in 20-25 fractions to small animals with more than 95% survival rates.
