An irradiation device using ionizing radiation, particularly for radiation therapy and/or radiation biology, simultaneously includes: at least one unit (MER) for emitting ionizing radiation at least one dose-monitoring unit (MCD) at least one unit for detecting an ionizing radiation dose (MDD) and at least one monitoring and control system (SCC). The units (MER, MDD, MCD) and the system (SCC) are also intelligently interconnected therebetween so as to engage with one another and form an intelligent monitoring and adjustment loop, such as to controllably, precisely and desirably produce strong doses of ionizing radiation of at least 0.01 Gy, having a precision within at least one 1 μGy but preferably 1 n Gy, in strong dose rates up to 1000 Gy/s with power within a range of 1 to 50 Me V in very brief time intervals of at least 0.1 μs, preferably 1 ms.