MARJANOVIC, JASMINA,SHEPPARD, GEORGE,FIDANZE, STEVEN D.,HASVOLD, LISA,WANG, LE,MCCLELLAN, WILLIAM,LIU, DACHUN,HOLMS, JAMES,DAI, YUJIA,MCDANIEL, KEITH
申请号：
PE0026842015
公开号：
PE02002016A1
申请日:
2014.06.27
申请国别(地区):
PE
年份:
2016
代理人:
摘要：
Relating to compounds of formula (i), where RX and ry are h RX1 is CN, A1, A2, A3, and A4 are n, L1 is o, NH, among others and G1 is phenyl, C3 C6 cycloalkyl, among others.These compounds are useful as agents in the treatment of diseases and clinical States, including inflammatory diseases, cancer, and AIDS.Also provided are Pharmaceutical compositions comprising one or more compounds of formula (i)Referida a compuestos de formula (I), done Rx y Ry son H Rx1 es -CN, A1, A2, A3, y A4 son N, L1 es O, NH, entre otros y G1 es fenilo, C3-C6 cicloalquilo, entre otros. Dichos compuestos son utiles como agentes en el tratamiento de enfermedades y estados clinicos, incluyendo enfermedades inflamatorias, cancer, y SIDA. Tambien se proveen composiciones farmaceuticas que comprenden uno o mas compuestos de formula (I)
