The present invention provides a kind of these configurations of transdermal formulation, so as to form adhesive phase on the carrier material of drug, described adhesive layer includes at least one thermoplastic elastomer (TPE) and high-grade aliphatic ester, and the content also containing tackifier absolute atmosphere is 10% weight % or less. The transdermal formulation adheres on skin, small to skin irritation, drug solubility and good Release Properties.
