CHO, YONG SEO,조용서,MIN, SUN JOON,민선준,LEE, JAE KYUN,이재균,PAE, AE NIM,배애님,RHIM, HYE WHON,임혜원,CHOI, KEE HYUN,최기현,SEO, SEON HEE,서선희,SONG, CHI MAN,송치만,CHOI, YEON HEE,최연희
申请号：
KR1020110016787
公开号：
KR1020120097287A
申请日:
2011.02.24
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A pharmaceutical composition containing pyrazoyl piperidine compounds and pharmaceutically acceptable salt thereof is provided to prevent or treat brain diseases, heard diseases, cancer, and pain.CONSTITUTION: A pyrazoyl piperidine compound is denoted by chemical formula 1. A pharmaceutical composition for treating cerebral diseases, cardiac diseases, cancer, or pain contains the compound of chemical formula 1 as an active ingredient. A method for preparing the compound comprises: a step of reacting piperidine acetate of chemical formula 2 and pyrazole methyl amine of chemical formula 3 of a step of reacting piperidine compound of chemical formula 4 with an aldehyde compound of chemical formula 5 by reduction-amination.COPYRIGHT KIPO 2013[Reference numerals] (AA) Reductive amination본 발명은 T-형 칼슘 채널에 대하여 약학적 활성을 보이는 피라조일 피페리딘 화합물 및 약제학적으로 허용 가능한 이의 염, 그리고 이들 화합물이 유효성분으로 함유된 약제조성물에 관한 것이다.
