שיטות לטיפול במחלה או הפרעה על ידי פורמולציה פומית של אנלוגים של ציטידין בשילוב עם נוגדן אנטי pd1 או אניטי pdl1 מונוקלונלי
- 专利权人:
- CELGENE CORPORATION
- 发明人:
- 申请号：
- IL25088717
- 公开号：
- IL250887D0
- 申请日:
- 2017.03.02
- 申请国别(地区):
- IL
- 年份:
- 2017
- 代理人:
- 摘要：
- The present disclosure provides methods of treating diseases or disorders with oral cytidine analogs (e.g., 5-azacytidine) in combination with anti-PD1/anti-PDL1 antibodies (e.g., pembrolizumab or durvalumab). The diseases or disorders include, but are not limited to, relapsed or refractory myelodysplastic syndromes, acute myeloid leukemia, ovarian cancer, or non-small cell lung cancer.
- 来源网站：
- 中国工程科技知识中心
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相关专利
- METHODS FOR TREATING A DISEASE OR DISORDER USING ORAL FORMULATIONS OF CYTIDINE ANALOGS IN COMBINATION WITH AN ANTI-PD1 OR ANTI-PDL1 MONOCLONAL ANTIBODY
- Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-PD1 or anti-PDL1 monoclonal antibody
- -PD1 -PDL1 METHODS FOR TREATING A DISEASE OR DISORDER USING ORAL FORMULATIONS OF CYTIDINE ANALOGS IN COMBINATION WITH AN ANTI-PD1 OR ANTI-PDL1 MONOCLONAL ANTIBODY
- Method for treating diseases or disorders using oral preparations of cytidine analogues in combination with anti-PD1 or anti-PDL1 monoclonal antibodies
- METHODS OF TREATING DISEASES OR DISORDERS USING COMPOSITIONS FOR ORAL APPLICATION CONTAINING CYTIDINE ANALOGUES IN COMBINATION WITH MONOCLONAL ANTIBODY TO PD1 OR PDL1
