Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-PD1 or anti-PDL1 monoclonal antibody

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专利权人:

Celgene Corporation

发明人:

Fandi, Abderrahim,Reiser, David,Barton, Debora,Begic, Damir

申请号：

AU2015315435

公开号：

AU2015315435A1

申请日:

2015.09.08

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present disclosure provides methods of treating diseases or disorders with oral cytidme analogs (e.g., 5-azacyddme) in combination with anti-PDl/anti-PDLl antibodies (e.g., pembrolizumab or durvalumab). The diseases or disorders include, but are not limited to, relapsed or refractory myelodysplastic syndromes, acute myeloid leukemia, ovarian cancer, or non-small cell lung cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/