A medical device comprises a pistol-shaped handle (2-4), a surgical end effector (1, 20, 30) connected to a distal end of a shaft extending from the handle (2-4), a surgical procedure actuator (3) for carrying out a surgical procedure on tissue at the surgical end effector (1, 20, 30), and a rotating knob at the handle (2-4). The rotating knob is rotatable with respect to the shaft about a shaft axis and is operable to operate the surgical procedure actuator and effect the surgical procedure.
