Synthesis and analysis of novel compounds that induce differentiation of human mesenchymal stem cells into hepatocytes

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专利权人:

カノンキュア株式会社;国立大学法人鳥取大学;学校法人東京女子医科大学

发明人:

汐田 剛史,星川 淑子,松本 則子,松見 吉朗,森本 稔,殿井 貴之,斎本 博之,大橋 一夫,岡野 光夫

申请号：

JP2017128831

公开号：

JP6391067B2

申请日:

2017.06.30

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

The purpose is to select low-molecular-weight compounds which are effective in inducing differentiation of mesenchymal stem cell into hepatocyte and to develop a safe differentiation-inducing method having excellent efficiency of differentiating mesenchymal stem cell into hepatocyte. Provided are at least one compound selected from the group consisting of compounds represented by formulae (1) and (2), a salt thereof, or a solvate of them； a differentiation inducer comprising at least one compound selected from the group consisting of compounds represented by formulae (1) and (2), a salt thereof, or a solvate of them； and a differentiation inducer comprising a compound represented by formula (8), a salt thereof, or a solvate of them.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/