PROBLEM TO BE SOLVED: To select an effective low molecular weight compound inducing differentiation from mesenchymal system stem cells to liver cells for developing a safe differentiation inducing method excellent in differentiation efficiency from the mesenchymal system stem cells to the liver cells.SOLUTION: A differentiation inducing agent inducing differentiation from mesenchymal stem cells to liver cells includes an organic low molecular weight compound controlling the Wnt/β-catenin pathway.