COMPOSÉS AMINOHÉTÉROARYLE À SUBSTITUTION THIAZOLE UTILISÉS COMME INHIBITEURS DE LA TYROSINE KINASE SPLÉNIQUE

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专利权人:

Merck Sharp & Dohme Corp.;Merck Canada Inc.

发明人:

申请号：

EP14872226.7

公开号：

EP3083559A4

申请日:

2014.12.18

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein ring R1, R2, R3, R4, ring B, and the subscript r are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).

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