COMPOSÉS AMINOHÉTÉROARYLE À SUBSTITUTION THIAZOLE INHIBITEURS DE TYROSINE KINASE SPLÉNIQUE

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专利权人:

MERCK SHARP & DOHME CORP.;MERCK CANADA INC.

发明人:

ANTHONY, NEVILLE, J.,ANDRESEN, BRIAN, M.,NORTHRUP, ALAN, B.,CHILDERS, KALEEN, K.,DONOFRIO, ANTHONY,MILLER, THOMAS, A.,LIU, YUAN,MACHACEK, MICHELLE, R.,WOO, HYUN CHONG,SPENCER, KERRIE, B.,ELLIS, JOHN M

申请号：

EP14788026

公开号：

EP2988744A4

申请日:

2014.04.22

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and R4 are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).

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http://www.ckcest.cn/home/