John W. Butcher;Joel S. Robichaud;Brian M. Andresen;Kenneth L. Arrington;MERCK SHARP & DOHME CORP.;John Michael Ellis;Jean-Francois Fournier;Ryan D. Otte;Alan B. Northrup;Jacques Yves Gauthier
发明人:
Brian M. Andresen,Kenneth L. Arrington,Ryan D. Otte,John Michael Ellis,John W. Butcher,Alan B. Northrup,Joel S. Robichaud,Jacques Yves Gauthier,Jean-Francois Fournier
申请号：
US15105713
公开号：
US09822107B2
申请日:
2014.12.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein ring R1, R2, R3, R4, ring B, and the subscript r are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
