Yuan LIU;Neville J. ANTHONY;Michelle R. MACHACEK;Hyun Chong WOO;Kerrie B. SPENCER;Kaleen K. CHILDERS;Thomas A. MILLER;John Michael ELLIS;Anthony FRIO;Micheal D. ALTM;Brain M. ANDERSEN;Alan B. NORTHRUP
发明人:
Neville J. Anthony,Brian M. Andresen,Alan B. Northrup,Kaleen K. Childers,Anthony Donofrio,Thomas A. Miller,Yuan Liu,Michelle R. Machacek,Hyun Chong Woo,Kerrie B. Spencer,John Michael Ellis,Michael D.
申请号:
US14786464
公开号:
US20160060255A1
申请日:
2014.04.22
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and R4 are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).