National Institutes of Biomedical Innovation, Health and Nutrition;Genedesign, Inc.
发明人:
申请号：
EP15872274.4
公开号：
EP3238727A1
申请日:
2015.12.24
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Provided are non-aggregating immunostimulatory oligonucleotides. The present invention also provides a delivery agent for an immunostimulatory-oligonucleotide nucleic acid medicine, said delivery agent including a nucleic acid that contains a phosphorothioated nucleotide. According to another aspect, the present invention further provides an oligonucleotide including a bioactive core, and a nucleic acid that contains a phosphorothioated nucleotide. The present invention yet further provides an immunostimulator including the bioactive core of a type A/D, type B/K, or type C immunostimulatory oligonucleotide.
