DERIVES DE TRIPTOLIDE POUR LA MODULATION DE L'APOPTOSE ET DE L'IMMUNOSUPPRESSION

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专利权人:

PHARMAGENESIS; INC.

发明人:

DAI, DONGCHENG,MUSSER, JOHN H.,LENNOX, EDWIN S.

申请号：

CA2485794

公开号：

CA2485794C

申请日:

2003.05.29

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Variously substituted carbonate and carbamate derivatives of triptolidecompounds have good aqueous solubility and convert to biologically activecompounds in vivo, at a rate which can be modulated by varying thesubstitution on the prodrug. The prodrugs are useful as immunosuppressive,anti-inflammatory and anticancer agents.

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