PROBLEM TO BE SOLVED: To produce an ACE inhibitor using inexpensive raw material and in a short time.SOLUTION: An ACE inhibitor has inhibitory activity on ACE, the inhibitor obtained by applying pressurization treatment to a mixture obtained by adding water to at least one of sake lees and shochu lees under the pressure condition of 10-500 MPa.COPYRIGHT: (C)2016,JPO&INPIT【課題】安価な原料を用い、かつ短時間で製造する。【解決手段】酒粕及び焼酎粕の少なくとも一方に水を加えた混合物を10~500MPaの圧力条件にて加圧処理を行うことで得られるACEに対して阻害活性を有するACE阻害剤。【選択図】図1