8 - carbamoyl Derivatives of 2 - (2,3 - pirid - 6-yl di substituted) - 1,2,3,4 - tetrahidroisoquinolina agents as inducers of Apoptosis for the treatment of Cancer and Immune and autoimmune diseases
LE WANG,GEORGE DOHERTY,XILU WANG,4. ZHI-FU TAO,MILAN BRUNCKO,AARON R. KUNZER,MICHAEL D. WENDT,XIAOHONG SONG,ROBIN FREY,TODD M. HANSEN,GERARD M. SULLIVAN,ANDREW JUDD,ANDREW SOUERS
申请号:
GT201400064
公开号:
GT201400064A
申请日:
2014.04.10
申请国别(地区):
GT
年份:
2014
代理人:
摘要:
The present Invention relates to compounds that inhibit the activity of Proteins antiapopt u00d3ticas BCL XL, compositions containing such compounds and Methods for treating diseases in which the proteins are expressed antiapopt u00d3ticas BCL XLLA PRESENTE INVENCIÓN SE RELACIONA CON COMPUESTOS QUE INHIBEN LA ACTIVIDAD DE LAS PROTEÍNAS ANTIAPOPTÓTICAS BCL-XL, CON COMPOSICIONES QUE CONTIENEN DICHOS COMPUESTOS Y CON MÉTODOS PARA TRATAR ENFERMEDADES EN LAS QUE SE EXPRESAN LAS PROTEÍNAS ANTIAPOPTÓTICAS BCL-XL