8 - carbamoyl Derivatives of 2 - (2,3 - pirid - 6-yl di substituted) - 1,2,3,4 - tetrahidroisoquinolina agents as inducers of Apoptosis for the treatment of Cancer and Immune and autoimmune diseases
XILU WANG,LE WANG,AARON R. KUNZER,MICHAEL D. WENDT,GERARD M. SULLIVAN,GEORGE DOHERTY,TODD M. HANSEN,ANDREW SOUERS,ZHI-FU TAO,MILAN BRUNKO,XIAOHONG SONG,ROBIN FREY,ANDREW JUDD
申请号:
DO2014000070
公开号:
DOP2014000070A
申请日:
2014.04.09
申请国别(地区):
DO
年份:
2014
代理人:
摘要:
Compounds that inhibit the activity of the antiapoptotic Protein BCL XL, compositions containing such compounds and Methods for treating diseases in which expressing the antiapoptotic Protein BCL XL.Compuestos que inhiben la actividad de las proteínas antiapoptóticas Bcl-xL, composiciones que contienen dichos compuestos y métodos para tratar enfermedades en las que se expresan las proteínas antiapoptóticas Bcl-xL.