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PEPTIDE, PHARMACEUTICAL COMPOSITION AND MEDICAMENT COMPRISING THEREOF, METHOD FOR THE TREATMENT AND/OR PREVENTION OF DIABETES AND DISEASES ASSOCIATED WITH OBESITY, METHOD FOR REDUCTION IN APPETITE, REDUCTION IN FOOD INTAKE OR REDUCTION OF CALORIE INTAKE
专利权人:
IMPERIAL INNOVATIONS LIMITED
发明人:
Bloom, Stephen, Robert,Блум Стівен Роберт
申请号：
UA200907137
公开号：
UA102370C2
申请日:
2007.12.13
申请国别(地区):
UA
年份:
2013
代理人:
摘要：
The invention relates to a peptide comprising an amino acid sequence Xaa1 Xaa2 Xaa3 Gly4 Thr5 Phe6 Thr7 Ser8 Asp9 Tyr10 Ser11 Lys12 Tyr13 Leu14 Xaa15 Xaa16 Xaa17 Xaa18 Xaa19 Xaa20 Xaa21 Xaa22 Xaa23 Xaa24 Trp25 Leu26 Xaa27 Xaa28 Xaa29 Xaa30 Xaa31 Xaa32 Lys33 Asn34 Asn35 Ile36 Ala37 wherein Xaa1 is D-His1 or His1, Xaa2 is Ala2 or Ser2, Xaa3 is Gln3 or Asp3, Xaa15 Xaa16 Xaa17 Xaa18 Xaa19 Xaa20 Xaa21 Xaa22 Xaa23 Xaa24 is: Glu15 Gln16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Ile23 Gln24, Glu15 Glu16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Leu23 Glu24, Glu15 Glu16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Leu23 Gln24, Glu15 Glu16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Ile23 Glu24, Glu15 Glu16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Ile23 Gln24, Glu15 Glu16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Leu23 Glu24, Glu15 Glu16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Leu23 Gln24, Glu15 Glu16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Ile23 Glu24, Glu15 Gln16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Leu23 Glu24, Glu15 Gln16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Leu23 Gln24, Glu15 Gln16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Ile23 Glu24, Glu15 Gln16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Leu23 Glu24, Glu15 Gln16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Leu23 Gln24 or Glu15 Gln16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Ile23 Glu24 Xaa27 Xaa28 Xaa29 Xaa30 Xaa31 Xaa32 is: Lys27 Asn28 Ala29 Gly30 Pro31 Ser32, or Lys27 Asn28 Gly29 Gly30 Pro31 Ser32 or a peptide as given above wherein Asn34 residue is replaced with Asp34, or a peptide as given above wherein Xaa3 is Glu33, to use of peptide as appetite suppressor, and for the treatment and/or prevention obesity, diabetes and/or diseases associated with obesity.Винахід належить до пептиду, що включає нижченаведену послідовність амінокислотXaa1 Xaa2 Xaa3 Gly4 Thr5 Phe6 Thr7 Ser8 Asp9 Tyr10 Ser11 Lys12 Tyr13 Leu14Xaa15 Xaa16 Xaa17 Xaa18 Xaa19 Xaa20 Xaa21 Xaa22 Xaa23 Xaa24 Trp25 Leu26Xaa27 Xaa28 Xaa29 Xaa30 Xaa31 Xaa32 Lys33 Asn34 Asn35 Ile36 Ala37де:Xaa1 являє собою D-His1 або His1,Xaa2 являє собою
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
