Gerwin Jan Puppels,Elisa Maria Barroso,Tom Christian Bakker Schut,Roeland W.H. Smits,Peter Jacobus Caspers,Senada Koljenovic
申请号：
US16069773
公开号：
US20180317818A1
申请日:
2016.01.18
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Method and instrument for analysing a tissue sample. Localized concentrations of an analyte are measured at a plurality of spaced apart locations around a controlled depth. Spatial variance of the analyte is calculated based on the measured analyte concentrations. The procedure is repeated while varying the controlled depth to obtain the spatial variance as a function of depth. Tissue at a particular depth may be evaluated as tumour tissue when the spatial variance is below the threshold. For example, a section distance is calculated between the tissue surface and a depth where the measured spatial variance crosses a predetermined threshold variance. Feedback can be provided based on a comparison between a calculated section distance and a pre-set minimum section margin.
