Disclosed are devices, arrangements and methods for quantifying the concentration of an analyte present in bodily fluid, including: an assay pad having at least one chemical reagent capable of producing a detectable signal in the form of a reaction spot upon reaction with the analyte； a light source； a detector array； a processor； and a memory in communication with the processor, the memory comprising: (a) at least one value indicative of one or more of: (i) the level of hematocrit contained in the sample； (ii) the volume of the sample applied to the assay pad； or (iii) imperfections present in the reaction spot； and (b) at least one algorithm for calculating the concentration of the analyte contained in the sample.
