A computer-implemented system and method for fast, reliable and automated processing for intima-media thickness (IMT) measurements. Various embodiments include receiving biomedical imaging data and patient demographic data corresponding to a current scan of a patient checking the biomedical imaging data in real-time to determine if an artery of the patient has a calcium deposit in a proximal wall of the artery acquiring arterial data of the patient as a combination of longitudinal B-mode and transverse B-mode data using a data processor to automatically recognize the artery using the data processor to calibrate a region of interest around the automatically recognized artery and determining the intima-media thickness (IMT) of an arterial wall of the automatically recognized artery.
