TRUSTEES OF TUFTS COLLEGE;THE UNIVERSITY OF MASSACHUSETTS FOUNDATION, INC.
发明人:
ZHANG XIAOHUI,KAPLAN DAVID L.,WHARRAM SCOTT E.,MCCARTHY STEPHEN
申请号:
IN445DEN2012
公开号:
IN445DEN2012A
申请日:
2012.01.16
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to the processes of preparing silkfibroin/polyethyen oxida blended materials, and the resulting materials thereof, which are suitable for biomedical applications such as wound healing. In particular, the electrospun silk fibroin/PEO mats with a silk:PEO blend ratio of 2:1 to 4:1, treated with controlled evaporation, constraint-drying techniques, and/or alcohol treatment, and/or PEO extraction, demonstrate suitable physical and biofunctional properties, such as fiber structure, topography, absorption, water vapor transmission rates, oxygen permeation, and biodegradability, relevant to biomaterial systems with utility for wound dressings.