Xiaohui Zhang;David L. Kaplan;Scott E. Wharram;Stephen McCarthy
发明人:
Xiaohui Zhang,David L. Kaplan,Scott E. Wharram,Stephen McCarthy
申请号：
US13382967
公开号：
US08728498B2
申请日:
2010.07.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to the processes of preparing silkfibroin/polyethylene oxide blended materials, and the resulting materials thereof, which are suitable for biomedical applications such as wound healing. In particular, the electrospun silk fibroin/PEO mats with a silk:PEO blend ratio of 2:1 to 4:1, treated with controlled evaporation, constraint-drying techniques, and/or alcohol treatment, and/or PEO extraction, demonstrate suitable physical and biofunctional properties, such as fiber structure, topography, absorption, water vapor transmission rates, oxygen permeation, and biodegradability, relevant to biomaterial systems with utility for wound dressings.
