4-(2-FLUOROPHENYL)-3-(3-METHOXYBENZYL)-1H-1,2,4-TRIAZOL-5(4H)-0NE AND ITS USE AS A THERAPEUTIC AGENT FOR METABOLIC DISEASE AND DEGENERATIVE BRAIN DISEASE
The present invention provides 4-(2-fluorophenyl)-3-(3-methoxybenzyl)-1H-1,2,4-triazole-5(4H)-one, or a pharmaceutically acceptable salt thereof. And its use. The compounds according to the present invention show excellent effects on the inhibition of acetylcholinesterase and the inhibition of alpha-glucosidase, and thus show excellent effects on the prevention, improvement or treatment of degenerative brain diseases and/or metabolic diseases.본 발명은, 4-(2-플루오로페닐)-3-(3-메톡시벤질)-1H-1,2,4-트리아졸-5(4H)-온, 또는 이의 약학적으로 허용가능한 염과 이의 용도를 제공한다. 본 발명에 따른 화합물은 아세틸콜린에스테라제 억제와 알파-글루코시다아제 억제에 우수한 작용 효과를 보임으로써, 퇴행성 뇌질환 및/또는 대사성 질환의 예방, 개선 또는 치료에 우수한 효과를 나타낸다.
