A compound that has the structure in which m is 0, 1 or 2； n is 0, 1 or 2； Q is C or N； A is (CH2) x where x is 1 to 5 or A is (CH2) x1 where x1 is 1 to 5 with an alkenyl bond or an alkynyl bond interspersed at any point in the chain, or A is - (CH2) x2-O- (CH2) x3 -in which x2 is from 0 to 5 and x3 is from 0 to 5, with the proviso that at least one of x2 and x3 is different from 0； B is a bond or is (CH2) x4 in which x4 is 1 to 5； X is CH or N； R1 is H or alkyl； R2 is H, alkyl, alkoxy, halogen, amino or substituted amino or cyano； R2a, R2b and R2c may be the same or different and are selected from H, alkyl, alkoxy, halogen, amino or substituted amino or cyano； R3 is selected from arylalkyl, aryloxycarbonyl, alkyloxycarbonyl, alkynyloxycarbonyl, alkenyloxycarbonyl, arylcarbonyl, alkylcarbonyl, aryl, heteroaryl, cycloheteroalkyl, heteroarylcarbonyl, heteroaryl-heteroarylalkyl, alkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, alkoxycarbonylamino, aryloxycarbonylamino, heteroaryloxycarbonylamino, heteroaryl-heteroarylcarbonyl, alkylsulfonyl, alkenylsulfonyl, heteroaryloxycarbonyl, cycloheteroalkyloxycarbonyl, heteroarylalkyl, aminocarbonyl, substituted aminocarbonyl, alkylaminocarbonyl, arylaminocarbonyl, heteroarylalkyl, cycloheteroalkyl heteroarylalkyl； hydroxyalkyl, alkoxy, alcoxiariloxicarbonilo, arylalkyloxycarbonyl, alquilariloxicarbonilo, arylheteroarylalkyl, arilalquilarilalquilo, aryloxyarylalkyl, haloalcoxiariloxicarbonilo, alcoxicarbonilariloxicarbonilo, ariloxiariloxicarbonilo, arilsulfinilarilcarbonilo, ariltioarilcarbonilo, alcoxicarbonilariloxicarbonilo, arilalqueniloxicarbonilo, heteroariloxiarilalquilo, ariloxiarilcarbonilo, ariloxiaxilalquiloxicarbonilo, arilalqueniloxicarbonilo, arylalkylcarbonyl, ariloxialquiloxicarbonilo, arylalkylsulfonyl, arylthiocarbonyl, arylalkenylsulfonyl, heteroarylsulfonyl, arylsulfonyl, alkoxyarylalkyl, heteroarylalkoxycarbonyl, arylheteroarylalkyl, alkoxyarylcarbonyl, ariloxiheteroarilalquilo, heteroarilalq
